The problems with the pharmaceutical industry began early on with cocaine tooth drops. Drugs ads have been present for just as long as that to encourage people to seek medical advice to buy their product and fund their costly research and development. In the early 1700s and 1800s drug company’s were advertised in papers in ways that were exaggerated or deceptive. In the Twentieth century drugs were separated by two classes, “Medical drugs” and illegal drugs. By the 1900s the FDA issued ad regulations that required a “true statement of information in brief summary relating to the side effects, contraindications, and effectiveness.